The importance of oxidative stress in pathogenesis of type 1 diabetes: Determination of catalase activity in lymphocytes of diabetic patients | Zendy

Saša Živić | Zendy; Jovan Vlaški | Zendy; Gordana Kocić | Zendy; Milica Pešić | Zendy; Vesna Ćirić | Zendy; Zlatko Djurić | Zendy

Open Access

The importance of oxidative stress in pathogenesis of type 1 diabetes: Determination of catalase activity in lymphocytes of diabetic patients

Author(s) -

Saša Živić,

Jovan Vlaški,

Gordana Kocić,

Milica Pešić,

Vesna Ćirić,

Zlatko Djurić

Publication year - 2008

Publication title -

medicinski pregled

Language(s) - English

Resource type - Journals

eISSN - 1820-7383

pISSN - 0025-8105

DOI - 10.2298/mpns0810458z

Subject(s) - catalase , oxidative stress , diabetes mellitus , endocrinology , pathogenesis , medicine , antioxidant , oxidative phosphorylation , enzyme , biochemistry , chemistry

Type 1 diabetes is a protoype of disease with an intensive oxidative stress. The oxidative stress means disturbing dynamic balance between prooxidants and antioxidants, either due to the increased production of the oxygen free radicals or the decreased antioxidant activity. The antioxidative enzyme catalase diminishes free radical hydrogen-peroxyde, which can be very toxic to pancreatic cells.

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