PEG mediated synthesis of 6-pyrazinyl-/fused pyrazinylquinazolin-4(3H)-ones using Castro-Stephen coupling, oxidation and cyclocondensation reactions | Zendy

Shankaraiah Pagilla | Zendy; A. Kishore Kumar | Zendy; V. Sunitha | Zendy; Anagani Kanaka Durga Bhavani | Zendy

Open Access

PEG mediated synthesis of 6-pyrazinyl-/fused pyrazinylquinazolin-4(3H)-ones using Castro-Stephen coupling, oxidation and cyclocondensation reactions

Author(s) -

Shankaraiah Pagilla,

A. Kishore Kumar,

V. Sunitha,

Anagani Kanaka Durga Bhavani

Publication year - 2020

Publication title -

journal of the serbian chemical society

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.227

H-Index - 45

eISSN - 1820-7421

pISSN - 0352-5139

DOI - 10.2298/jsc190517014p

Subject(s) - chemistry , coupling reaction , alkyne , potassium permanganate , coupling (piping) , quinazolinone , peg ratio , medicinal chemistry , combinatorial chemistry , organic chemistry , catalysis , materials science , metallurgy , finance , economics

PEG mediated green synthesis of 6-pyrazinyl-/fused pyrazinylquinazolin-4(3H)-ones was developed starting from 6-iodo-3-methyl-2-phenylquinazolin-4(3 H )-one by means of quinazolinone based internal alkyne/1,2-diketone as intermediates using Castro-Stephen coupling reaction / potassium permanganate mediated oxidation and cyclocondensation reactions.

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