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PEG mediated green synthesis of 6-pyrazinyl-/fused pyrazinyl­qu­i­nazolin-4(3H)-ones was developed starting from 6-iodo-3-methyl-2-phenyl­quinazolin-4(3 H )-one by means of quinazolinone based internal alkyne/1,2-di­ketone as intermediates using Castro-Stephen coupling reaction / potassium permanganate mediated oxidation and cyclocondensation reactions.

PEG mediated synthesis of 6-pyrazinyl-/fused pyrazinylquinazolin-4(3H)-ones using Castro-Stephen coupling, oxidation and cyclocondensation reactions