Solubility and degradation of paracetamol in subcritical water | Zendy

Zuhal Emire | Zendy; Erdal Yabalak | Zendy; Özkan Görmez | Zendy; A. Murat Gizir | Zendy

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Solubility and degradation of paracetamol in subcritical water

Author(s) -

Zuhal Emire,

Erdal Yabalak,

Özkan Görmez,

A. Murat Gizir

Publication year - 2016

Publication title -

journal of the serbian chemical society

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.227

H-Index - 45

eISSN - 1820-7421

pISSN - 0352-5139

DOI - 10.2298/jsc160520079e

Subject(s) - solubility , degradation (telecommunications) , chemistry , bar (unit) , mole fraction , chromatography , organic chemistry , geology , telecommunications , oceanography , computer science

In this study, solubility and degradation of paracetamol were examined using subcritical water. Effect of temperature and static time was investigated during solubility process in subcritical water at constant pressure (50 bar). Experimental results show that temperature and static time have crucial effect on the degradation and solubility rates. Maximum mole fraction for solubility of paracetamol was obtained at 403 K as (14.68 ± 0.74)×103. Approximation model for solubility of paracetamol was proposed. O2 and H2O2 were used in degradation process of paracetamol. Maximum degradation rate was found as 68.66 ± 1.05 and 100 ± 0.00 % using O2 and H2O2, respectively

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