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Facile synthesis and antifungal activity of dithiocarbamate derivatives bearing an amide moiety
Author(s) -
Yuwen Li,
Shu-Tao Li
Publication year - 2015
Publication title -
journal of the serbian chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.227
H-Index - 45
eISSN - 1820-7421
pISSN - 0352-5139
DOI - 10.2298/jsc150114047l
Subject(s) - alternaria solani , moiety , amide , chemistry , dept , fusarium solani , dithiocarbamate , carbon 13 nmr , proton nmr , fusarium , stereochemistry , organic chemistry , nuclear chemistry , fungicide , microbiology and biotechnology , biology , botany
A series of novel dithiocarbamate derivatives bearing amide moiety 3a-3i and 4a-4i were synthesized by a facile method, and the structures of these derivatives were confirmed by 1H NMR, 13C NMR, elemental analysis and high-resolution mass spectrometry (HRMS). Their antifungal activity against five phytopathogenic fungi were evaluated, and the results showed that most of the target compounds displayed low antifungal activity in vitro against Gibberella zeae, Cytospora sp., Collectotrichum gloeosporioides, Alternaria solani, and Fusarium solani at concentration of 100 mg/L. Compound 4f and 4g exhibited significant activity against Alternaria solani and Collectotrichum gloeosporioides, respectively

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