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In this study the degradation of Methyl Orange, using Fenton reaction was  studied and optimized using central composite design as a response surface  methodology. The effects of various experimental parameters in this reaction  were investigated using central composite design. 28 experiments, with 4  factors and 5 levels for each factor were designed. These factors (or  variables) were: initial concentration of Fe (II), initial concentration of  H2O2, initial concentration of oxalate and the reaction time. A  full-quadratic polynomial equation between the percentage of dye degradation  (as a response) and the studied parameters was established. After removing  the non-significant variables from the model, response surface method was  used to obtain the optimum conditions. The optimum ranges of variables were:  0.25 - 0.35 mM for initial concentration of Fe (II), 5-17 mM for initial  concentration of H2O2, 4-9 mM for initial concentration of oxalate, and 50-80  min for the reaction time. Also the results of extra experiments showed that  these optimized values can be used for real samples and yield to a high value  for the response

Central composite design for the optimization of removal of the azo dye, methyl orange, from waste water using fenton reaction