Chemical composition and biological activity of the acetone extract of Ambrosia artemisiifolia L. pollen

In this study, the chemical components, antimicrobial and genotoxic biological activities of the acetone extract of Ambrosia artemisiifolia L. pollen were examined. Two lactones were identified: ambrosin and artesovin. The antimicrobial activity of the acetone extract of A. artemisiifolia L. pollen was examined on ten different bacterial species using the disc diffusion method and the microdilution method in Mueller-Hinton broth dilution. The minimal inhi- bitory concentration of the acetone extract of A. artemisiifolia pollen varied be- tween 1.25−6.50 mg mL -1 . The genotoxic effect of the acetone extract of A. artemisiifolia pollen on a eukaryotic model system Drosophila melanogaster was investigated using the SLRL test.