Synthesis and biological activity evaluation of new functionally substituted 5-arylidene-2,4-dioxotetrahydro-1,3-thiazoles | Zendy

Katarina Popov-Pergal | Zendy; Milica Rančić | Zendy; Miroslav Pergal | Zendy; Gordana Bogdanović | Zendy; Vesna Kojić | Zendy; Dejan Djoković | Zendy

Open Access

Synthesis and biological activity evaluation of new functionally substituted 5-arylidene-2,4-dioxotetrahydro-1,3-thiazoles

Author(s) -

Katarina Popov-Pergal,

Milica Rančić,

Miroslav Pergal,

Gordana Bogdanović,

Vesna Kojić,

Dejan Djoković

Publication year - 2006

Publication title -

journal of the serbian chemical society

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.227

H-Index - 45

eISSN - 1820-7421

pISSN - 0352-5139

DOI - 10.2298/jsc0609861p

Subject(s) - thiazole , chemistry , cytotoxicity , fibroblast , in vitro , cell culture , combinatorial chemistry , stereochemistry , biochemistry , biology , genetics

New functionally substituted 5-arylidene-2,4-dioxotetrahydro 1,3-thiazole- 3-carboxylic acid cholesteryl esters were synthesized from 2,4-dioxotetrahydro- 1,3-thiazole and evaluated for their in vitro cytotoxicity against several human tumor cell lines and one normal lung fibroblast cell line.

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