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In this paper a comparison of the chemical composition and antimicrobial action of the ethanol extracts from the flower, leaf and stem of the herbal species Salvia officinalis L. (Lamiaceae), originating from the southeast region of Serbia was carried out. The chemical composition of the extracts was determined by GC-FID and GC-MS analyses. Manool has the highest level of all the components (9.0-11.1 %). Antimicrobial activity was determined by the diffusion and dilution method, whereby the latter one was modified by use of cellu- lose discs, and it was applied for the determination of the minimal inhibitory (MIC) and min- imal lethal concentrations (MLC). The leaf extract has a stronger antimicrobial activity than those of the flower and stem.

Chemical constituents and antimicrobial activity of the ethanol extracts obtained from the flower, leaf and stem of Salvia officinalis L