Synthesis and biological activity of some heterocyclic compounds containing quinoxaline and coumarin moieties
Author(s) -
Ibrahim M. ElDeen,
Abd El-Fattah
Publication year - 2000
Publication title -
journal of the serbian chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.227
H-Index - 45
eISSN - 1820-7421
pISSN - 0352-5139
DOI - 10.2298/jsc0002095e
Subject(s) - quinoxaline , hydrazide , chemistry , coumarin , derivative (finance) , combinatorial chemistry , medicinal chemistry , organic chemistry , economics , financial economics
2,3-Dichloroquinoxaline (2) condensed with 7,8-dihydroxy-4-methylcoumarin to give the 1,4-dioxane derivative 4. 2.3-Dichloroquinoxaline (2) reacted with 4-hydroxycoumarin, 7-hydroxy-4-methylcoumarin and acyl hydrazide 13 to give either the 2,3-(dicoumarin-4-yloxy)quinoxaline (6) or the2,3-di-(4-methylcoumarin-7-yloxy)quinoxaline (7) or the 2-chloro-3-(coumarin-4-yloxy)quinoxaline (8) or the 2-chloro-3-(4methylcoumarin-7-yloxy) quinoxaline (9) or the ditriazoloquinoxaline 14 or the oxadiazinoquinoxaline 16, depending on the relative ratios of the reactants and the reaction conditions.
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