Salivary carcinoembryonic antigen as an inflammatory marker | Zendy

Snežana Golubović | Zendy; Ljiljana Janković | Zendy; Aris Movsesijan | Zendy; Žanka BojićTrbojević | Zendy; Miroslava Janković | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Salivary carcinoembryonic antigen as an inflammatory marker

Author(s) -

Snežana Golubović,

Ljiljana Janković,

Aris Movsesijan,

Žanka BojićTrbojević,

Miroslava Janković

Publication year - 2003

Publication title -

jugoslovenska medicinska biohemija

Language(s) - English

Resource type - Journals

eISSN - 1452-8193

pISSN - 0354-3447

DOI - 10.2298/jmh0303207g

Subject(s) - carcinoembryonic antigen , saliva , medicine , gastroenterology , periodontitis , periodontal disease , stage (stratigraphy) , immunology , cancer , biology , paleontology

Summary: In this study we examined concentration of carcinoembryonic antigen (CEA) in paired saliva and serum samples from healthy individuals and patients with periodontal disease. CEA concentration was determined immunoradiometrically using highly specific anti-CEA antibodies. The salivas from periodontally healthy subjects revealed CEA concentrations with median value of 62 mg/L. Distribution of salivary CEA concentrations in patients with periodontal diseases were very broad with median values: 74 mg/L (stage I), 84 mg/L (stage II), 240 mg/L (stage III) and 412 mg/L (necrotizing ulcerative periodontitis-NUP). Analysis of the obtained values indicated statistically significant increase in salivary CEA, in subjects with periodontal diseases. Metronisadole treatment in patients with NUP leads to statistically significant decrease in salivary CEA. The results obtained suggested salivary CEA as a potential marker of the alterations of periodontium.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research