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Fruit is rich in different phenolic compounds which are recognized as   potential natural medicaments and have been used in folk medicine for   centuries. In order to evaluate phenol composition, cornelian cherry (Cornus   mas) fruit and leaf extracts were subjected to the spectrophotometric and   HPLC analysis. The radical scavenging activity was estimated using DPPH test   and antimicrobial activity by disc diffusion and microwell dilution tests.   All extracts showed high phenol content from 89.89 ± 0.45 to 117.34 ± 1.40 mg   f gallic acid equivalents GAE/g extract dry matter DM but different   composition of phenol compounds. Flavonols, anthocyanins, flavan-3-ols and   phenolic acids were the main phenol classes found in the investigated fruit   and leaf extracts. All extracts showed significant radical scavenging   activity and a correlation with total phenol content (R2 = 0.9832).   Significant antimicrobial activity was found against Gram-positive, followed   by Gram-negative strains, and yeast in all tested extracts. Cornelian cherry   fruit and leaf extracts, rich in phenolic content, with significant   antiradical and antimicrobial activity, can be used as additives in food and   medicaments. [Projekat Ministarstva nauke Republike Srbije, br. 34012, br.   31020 and br 176006 and EU, FP7 - Regpot - 2007- 3-01, the project   «Chromlab-Antioxidant», No. 204756

Phenol composition, DPPH radical scavenging and antimicrobial activity of cornelian cherry (Cornus mas) fruit and leaf extracts