Open AccessCyclosporine A (CsA) treatment of chronic autoimune-mediated keratoconjunctivitis sicca in dogs
Author(s) -
Milan Hadži-Milić,
Jelena Djordjević,
Nebojša Krstić
Publication year - 2013
Publication title -
acta veterinaria
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.308
H-Index - 17
eISSN - 1820-7448
pISSN - 0567-8315
DOI - 10.2298/avb1306677h
Subject(s) - keratoconjunctivitis sicca , medicine , conjunctiva , vernal keratoconjunctivitis , clinical efficacy , keratoconjunctivitis , dermatology , ophthalmology , surgery , pathology
The paper is a five year retrospective study of the efficacy of 0.2% Cyclosporine A eye cream in the treatment of chronic autoimmunemediated KCS in dogs. 114 dogs of 32 breeds, both sexes, and different ages with chronic autoimmune-mediated KCS were treated with 0.2% Cyclosporine A in the form of eye cream (Optimmune®, Schering - Plough Animal Health) applied to the lower lid conjunctiva at a dose of 6 mm length of the cream strip every 12 hours, during 90 days. Dogs treated with CsA had an improved STT score, specially dogs which had STT values >5 mm/min at the start. Improvement of the clinical picture and healing of superficial corneal lesions were also recorded