The effects of estrogen on the morphology of the pyramidal neurons of the parietal cortex of female rats
Author(s) -
Drekić Dmitar,
Lozance Olivera,
Nebojša Milovanović,
Mirko Kerkez,
D. Stefanović,
Zoric Zoran
Publication year - 2006
Publication title -
acta veterinaria
Language(s) - English
Resource type - Journals
eISSN - 1820-7448
pISSN - 0567-8315
DOI - 10.2298/avb0603215d
Subject(s) - soma , apical dendrite , dendrite (mathematics) , medicine , posterior parietal cortex , endocrinology , golgi apparatus , estrogen , cortex (anatomy) , biology , anatomy , chemistry , neuroscience , endoplasmic reticulum , microbiology and biotechnology , geometry , mathematics
In this study the effects of a neonatally (3rd day of life) administered single dose (1 mg) of estradiol dipropionate (E2) on the parietal cortex of juvenile (16 days of life) female rats were investigated. The morphology the volume of the soma and the thickness of the apical dendrite were studied in Golgi impregnated pyramidal neurons from both the external and internal pyramidal layers. In the treated female rats the volume of the soma and the thickness of the apical dendrite of pyramidal neurons was increased surpassing the values in the corresponding controls. These findings indicated significant and prolonged effects of a single dose of estrogen administered in the neonatal period, on the parietal neocortical pyramidal neurons of female rats
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