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Pulmonary granular cell tumors (GCTs) are uncommon and usually benign and  their coexistence with bronchogenic adenocarcinoma is rare. We report the  case of 50-year-old woman with GCT located in the left lung hilum, which  occurred simultaneously with a primary bronchogenic adenocarcinoma in the  same area. Contrast CT scan of the head revealed secondary deposits in the  right cerebellum, presumably of adenocarcinomas origin. Bronchoscopy revealed  narrowing on the beginning of the left lingular bronchus and infiltration of  the medial distal wall of the left main bronchus. Large tumor cells with  eosinophilic granular cytoplasm were seen on light microscopic examination.  Tumor cells fully occupied submucosa and had small, round nuclei with no  signs of pleomorphism. Immunohistochemically, these cells were S-100  positive. In small area, groups of atypical oval-shaped cells of  adenocarcinomas origin were noticed. This confirmed the diagnosis of GCT  coexisting with adenocarcinoma. After consultation with oncologists, the  patient was scheduled for further polychemotherapy and radiation treatment

Granular cell tumor of the bronchus coexisting with a bronchogenic adenocarcinoma: Case report