MicroRNA expression in non-Hodgkin's lymphomas | Zendy

Vladimir Baltić | Zendy; Milan Baltic | Zendy; Zorica Svirčev | Zendy; Vera Jerant-Patić | Zendy

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MicroRNA expression in non-Hodgkin's lymphomas

Author(s) -

Vladimir Baltić,

Milan Baltic,

Zorica Svirčev,

Vera Jerant-Patić

Publication year - 2008

Publication title -

archive of oncology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.104

H-Index - 13

eISSN - 1450-9520

pISSN - 0354-7310

DOI - 10.2298/aoo0804059b

Subject(s) - microrna , suppressor , cancer , lymphoma , biology , cancer research , function (biology) , gene , gene expression , non coding rna , messenger rna , genetics , immunology

MicroRNAs are a class of short, single-stranded, noncoding RNA molecules that negatively regulate the expression target mRNA at posttranslational level. microRNAs as key regulatory molecules play important biological function and might act as tumor suppressor oncogenes in cancer and lymphomas. microRNAs cause the expression of important cancer related genes and might prove useful in the diagnostics, prognosis, and treatment of some lymphomas This review focuses on the role of microRNAs in normal lymphocyte differentiation and in development of non-Hodgkin's lymphomas

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