Anaplastic large cell lymphoma | Zendy

Jelica Tiodorović | Zendy; Viktor Lazarević | Zendy; Milenko Stanojevic | Zendy; Dragan Jovanović | Zendy; Danica Tiodorović-Živković | Zendy

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Anaplastic large cell lymphoma

Author(s) -

Jelica Tiodorović,

Viktor Lazarević,

Milenko Stanojevic,

Dragan Jovanović,

Danica Tiodorović-Živković

Publication year - 2006

Publication title -

archive of oncology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.104

H-Index - 13

eISSN - 1450-9520

pISSN - 0354-7310

DOI - 10.2298/aoo0602054t

Subject(s) - cd30 , pathology , anaplastic large cell lymphoma , medicine , axilla , biopsy , lymphoma , immunohistochemistry , lymph node , bone marrow , trunk , biology , ecology , cancer , breast cancer

Anaplastic large cell lymphoma is defined by a proliferation of large pleomorphic blasts and a constant expression of the CD30 molecule on all neoplastic cells, and has been clinically subdivided into a primary form and a secondary form. We are presenting a case of 14-year-old boy with reddish-livid papules on the skin of right half of trunk that were confluent in the lower end into solid plaque with diameter 20 x 15 cm, and enlarged lymph nodes in axilla and on neck. Lesioned skin biopsy, biopsy of lymph node and bone marrow showed pleomorphic cells, strongly CD30, and ALK positive. In our patient diagnosis was reached on the basis of morphological and immunohistochemical characteristics

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