Micronucleus level in exfoliated buccal mucosa cells of cancer patients | Zendy

Armen Nersesyan | Zendy; Nina Vardazaryan | Zendy; A.G. Gevorgyan | Zendy; Rouben Arutyunyan | Zendy

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Micronucleus level in exfoliated buccal mucosa cells of cancer patients

Author(s) -

Armen Nersesyan,

Nina Vardazaryan,

A.G. Gevorgyan,

Rouben Arutyunyan

Publication year - 2002

Publication title -

archive of oncology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.104

H-Index - 13

eISSN - 1450-9520

pISSN - 0354-7310

DOI - 10.2298/aoo0201035n

Subject(s) - micronucleus test , buccal swab , micronucleus , buccal mucosa , medicine , buccal administration , cancer , genome instability , lung cancer , breast cancer , pathology , cancer research , biology , dna damage , oral cavity , microbiology and biotechnology , dentistry , dna , genetics , toxicity

Micronucleus levels in exfoliated buccal mucosa cells of patients with primary breast, lung, cervix uteri cancer, and patients with Hodgkin's disease were studied (n=59). Significantly increased number of micronuclei in cells of cancer patients was observed compared with healthy persons (n=45). The evaluation of micronuclei number in buccal mucosa cells shows genomic instability in somatic cells of humans

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