English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Plus monthly

Global: Zendy Tools annual

Global: Zendy Tools monthly

Global: Zendy Free Plan

The effects of a mixture of seven pesticides were examined on the expression   of antioxidant enzymes, Mn superoxide dismutase (Mn-SOD), catalase (CAT),   glutathione synthetase (GS), and heat shock proteins (HSP) 26, 60, 70 and 83   in adult fruit flies (Drosophila melanogaster Oregon R). The flies were   reared under controlled conditions on artificial diets and treated with a   mixture of seven pesticides (molinate, thiobencarb, linuron, phorate,   primiphos-methyl, fenvalerate and lambda-cyhalothrin) commonly found in   water, at concentrations of 0.1, 0.5 and 1 parts per billion (ppb) for 1 and   5 days. Quantitative real-time PCR (qRT-PCR) analysis of Mn-SOD, CAT and GS   expression revealed that the analyzed markers responded significantly to   pesticide-induced oxidative stress, in particular on the 5th day of   treatment. On the 1st day of treatment, the relative expression of HSP26 and   HSP60 genes increased only after exposure to the highest concentrations of   pesticides, whereas HSP70 and HSP83 expression increased after exposure to   0.5 and 1 ppb. After five days of treatment, the expression of all HSP genes   was increased after exposure to all pesticide concentrations. A positive   correlation was determined between the relative expression levels of some   HSPs (except HSP60), and antioxidant genes. The observed changes in   antioxidant enzyme and HSP mRNA levels in D. melanogaster suggest that the   permissible limits of pesticide concentrations for clean drinking water   outlined in the regulations of several countries are potentially cytotoxic.   The presented findings lend support for reevaluation of these limits

Responses of antioxidant enzymes and heat shock proteins in drosophila to treatment with a pesticide mixture