English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Tools annual

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Presents the access of premium content as premium feature

Premium Content

Global: Zendy Plus annual

Global: Zendy Free Plan

We analyzed the influence of inflammatory macrophages on the osteogenic   process in subcutaneous implants composed of mineral bone substitute.   Thioglycollate-elicited peritoneal macrophages (TEPMs) were characterized as   inflammatory. This was confirmed microscopically by the nitroblue tetrazolium   (NBT) test and the production of tumor necrosis factor α (TNF-α). The   implants (M-type) were made of mineral bone substitute (Bio-Oss®) mixed with   TEPMs and blood clot. Implants without macrophages served as the control   (C-type). Subcutaneous implantation in the interscapular area was performed   on BALB/c mice. Implants were extracted after 2 and 8 weeks. In M-type   implants, phagocytosis and angiogenesis were more pronounced, and   osteoblast-like cells aligned onto granules of implanted material and osteoid   structures can be seen. The observed higher osteocalcin and lower osteopontin   immunoexpression in M-type implants when compared to the control after 8   weeks suggest a more advanced osteogenic process. Our results indicate that   the presence of inflammatory macrophages in the composition of an implant may   have a beneficial effect on the osteogenic process. [Projekat Ministarstva   nauke Republike Srbije, br. III41017

Osteogenic effect of inflammatory macrophages loaded onto mineral bone substitute in subcutaneous implants