Direct correlation between the scores of PANSS/AIMS scales and some oxidative stress markers in treated schizophrenic patients | Zendy

Romeo Dobrin | Zendy; Irina Dobrin | Zendy; Cristinel Ștefănescu | Zendy; Alin Ciobîcă | Zendy; Lăcrămioara Șerban | Zendy; Emil Anton | Zendy

Open Access

Direct correlation between the scores of PANSS/AIMS scales and some oxidative stress markers in treated schizophrenic patients

Author(s) -

Romeo Dobrin,

Irina Dobrin,

Cristinel Ștefănescu,

Alin Ciobîcă,

Lăcrămioara Șerban,

Emil Anton

Publication year - 2014

Publication title -

archives of biological sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.217

H-Index - 25

eISSN - 1821-4339

pISSN - 0354-4664

DOI - 10.2298/abs1404559d

Subject(s) - oxidative stress , malondialdehyde , lipid peroxidation , superoxide dismutase , schizophrenia (object oriented programming) , glutathione peroxidase , correlation , antioxidant , clinical psychology , medicine , psychology , psychiatry , chemistry , biochemistry , geometry , mathematics

Oxidative stress is increasingly viewed as potentially important in the pathophysiology of schizophrenia, although most results regarding this subject are contradictory. We previously demonstrated an increased oxidative stress status in schizophrenic patients, regardless of their treatment. In this paper, we were interested in whether there is a correlation between the specific activities of the most important antioxidant enzymes (superoxide dismutase and glutathione peroxidase) and a lipid peroxidation marker (malondialdehyde) and the scores of PANSS/AIMS scales. A direct significant correlation was observed between oxidative stress markers and the aforementioned scales. Our results provide additional evidence regarding the implications of oxidative stress in patients with schizophrenia

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research