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Analysis of volatile organic compounds (VOCs) in human breath can provide   information about the current physiological state of an individual, such as   clinical conditions and exposure to exogenous pollutants. The blood-borne   VOCs present in exhaled breath offer the possibility of exploring   physiological and pathological processes in a noninvasive way. However, the   field of exhaled breath analysis is still in its infancy. We undertook this   study in order to define interindividual variation and common compounds in   breath VOCs of 48 young human volunteers. Alveolar breath samples were   analyzed by automated thermal desorption, gas chromatography with flame   ionization detector (FID) and electron capture detector (ECD) using SUPELCO   standards with 66 compounds. Predominant compounds in the alveolar breath of   analyzed subjects are ethylbenzene, 1-ethyl-4-methylbenzene,   1,2,4-trimethylbenzene and 1,3,5-trimethylbenzene (over 50% of the subjects).   Isopropyl alcohol, propylene, acetone, ethanol were found as well. We   detected substituted compounds in exhaled breath. [Projekat Ministarstva   nauke Republike Srbije, br. 172001

Analysis of human exhaled breath in a population of young volunteers