Pre-administration of vitamin C reduces exercise-induced oxidative stress in untrained subjects
Author(s) -
F. Trofin,
Marin Chirazi,
Cezar Honceriu,
Paula Drosescu,
Gabriela Grădinariu,
Alin Vorniceanu,
Emil Anton,
Dumitru Cojocaru,
Alin Ciobîcă,
Elena Ciornea,
I Cojocaru
Publication year - 2014
Publication title -
archives of biological sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.217
H-Index - 25
eISSN - 1821-4339
pISSN - 0354-4664
DOI - 10.2298/abs1403179t
Subject(s) - oxidative stress , malondialdehyde , lipid peroxidation , antioxidant , medicine , glutathione peroxidase , vitamin c , endocrinology , vitamin e , vitamin , glutathione , physical exercise , chemistry , enzyme , biochemistry , superoxide dismutase
We investigated the effects of a 40 min bout of bicycle exercise, and the effects of vitamin C administration 12 h before exercise, on the serum markers of oxidative stress in young untrained subjects. Increased levels of malondialdehyde, the marker of the lipid peroxidation, and a decrease in specific activity of the antioxidant enzyme glutathione peroxidase that were observed as a result of exercise, pointed to the presence of exercise-induced oxidative stress. These markers were reduced by pre-administration of vitamin C. The results suggest that physically active subjects could increase their daily dietary vitamin C intake in order to reinforce their antioxidant defenses prior to exercise training
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