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We investigated the effects of a 40 min bout of bicycle exercise, and the   effects of vitamin C administration 12 h before exercise, on the serum   markers of oxidative stress in young untrained subjects. Increased levels of   malondialdehyde, the marker of the lipid peroxidation, and a decrease in   specific activity of the antioxidant enzyme glutathione peroxidase that were   observed as a result of exercise, pointed to the presence of exercise-induced   oxidative stress. These markers were reduced by pre-administration of vitamin   C. The results suggest that physically active subjects could increase their   daily dietary vitamin C intake in order to reinforce their antioxidant   defenses prior to exercise training

Pre-administration of vitamin C reduces exercise-induced oxidative stress in untrained subjects