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The aim of this paper was to evaluate the effect of using artificial dermis   matrix plus autologous split-thickness skin (ADM and ASTS) in the treatment   of deep-burns in hands of severely burned patientsWe recruited a total of 58   patients with large area burns greater than 80% that were eschar-excised.   Twenty-eight of them were treated with ADM and ASTS (test group); 30 were   treated with autologous medium-thickness skin (AMTS) (control group). The   healing time of the hand wound was noted, clinical and photographic   evaluations were performed, and a Jebsen-Taylor hand function test was   compared and analyzed in the two groups. The wound healing time in the test   group (24.22±3.34 days) were longer than that of the control group   (13.42±3.36 days) and statistically significant. The healing time of skin   graft donor sites was shorter than that of the control group (7.14±1.63 vs.   14.28±2.37 days) and statistically significant (P<0.05). The 3rd and 6th   month follow-up with clinical and functional evaluations revealed no   differences between the two groups. In addition, there was no obvious scar   formation and less pigmentation in either group. The repair of deeply burned   hands with artificial dermis matrix was beneficial to both wound healing and   the donor site, and was beneficial to the whole body rehabilitation of   severely burned patients

Cografts of artificial dermis matrix and autogenetic split-thickness of repaired skin in severe hand wounds in patients with deep burns