English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

In this study we evaluated a methanol leaf extract of Vitex negundo L.  (Verbenaceae) for antitumor and antibacterial activities using the potato  disc bioassay and the agar disc diffusion method, respectively. Taking ≤20%  tumor inhibition as significant, we found significant crown gall inhibition  (24-48.39%) with 1 and 10 mg/ml extracts while 0.1 mg/ml of the extract was  ineffective (14.67% to 18.28%). Maximal tumor inhibition was observed with 10  mg/ml extract against Agrobacterium tumefaciens strain AtSl0105 (48.39%),  followed by AtTa0112 (45.9%) and AtAc0114 (44%). The methanol leaf extract  showed growth inhibitory potency against all of the studied bacteria  (Bacillus subtilis, Staphylococcus aureus, Pseudomonas aeruginosa,  Escherichia coli and Salmonella typhi). The minimum inhibitory concentrations  ranged from 0.312 mg/ml to 1.25 mg/ml. The least MIC value was recorded  against S. aureus and P. aeruginosa. The presented findings indicate that the  methanol leaf extract could be considered as a source of novel antitumor and  antibacterial compounds

Antitumor and antibacterial activity of a crude methanol leaf extract of Vitex negundo L.