The effect of fluoride on the serum level of calcium in the rat (Rattus norvegicus) | Zendy

Muhamed Fočak | Zendy; E. Hasković | Zendy; Damir Suljević | Zendy

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The effect of fluoride on the serum level of calcium in the rat (Rattus norvegicus)

Author(s) -

Muhamed Fočak,

E. Hasković,

Damir Suljević

Publication year - 2012

Publication title -

archives of biological sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.217

H-Index - 25

eISSN - 1821-4339

pISSN - 0354-4664

DOI - 10.2298/abs1204585f

Subject(s) - calcium , fluoride , endocrinology , body weight , medicine , chemistry , biology , inorganic chemistry

The effect of fluoride on the calcium level in serum was analyzed in the laboratory rat Rattus norvegicus. The control group consisted of 10, and the experimental group of 15 animals. In the experimental group, fluoride at a concentration of 3 mg/100 g body weight of rats was intramuscularly injected into the musculus gluteus maximus. The concentration of calcium was measured by the CPC method. The average serum calcium concentration was 2.46 mmol/l, with female rats having higher values of serum calcium than male rats. Fluoride caused the reduction of calcium concentration in serum (p<0.05); the reduction was significantly expressed in female rats (p<0.000)

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