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Extended time of cold ischemia and its influence on the physiological function of human adult pancreatic islets
Author(s) -
Dragan Nikolić,
Predrag Djordjević,
Dj Radak,
Vesna Lačković,
Miloš Bajčetić,
Gordana Milic,
Draško Gostiljac,
Mijailovic Sanja Ilic,
N. Raketić,
Vesna Stojiljković,
Nikica Grubor,
Milovan Jovanović,
Stojan Latinčić
Publication year - 2011
Publication title -
archives of biological sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.217
H-Index - 25
eISSN - 1821-4339
pISSN - 0354-4664
DOI - 10.2298/abs1104007n
Subject(s) - pancreatic islets , islet , ischemia , warm ischemia , cold ischemia , endocrinology , medicine , insulin , biology , reperfusion injury
In this study we compared the effects of duration of cold ischemia (longer and shorter ischemia) on the yield, viability and preservation of the physiological function and insulin secretion of adult human pancreatic islets in short-term (seven days) culture. Based on the tested parameters, we established that there are no major differences between these two test groups and that the storage and transport of pancreatic tissue in physiological solution at 4oC gives quite satisfactory results

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