Immunohistochemical detection of estrogen and progesterone receptors in the human lacrimal gland | Zendy

Jasmina Gligorijević | Zendy; Miodrag Krstić | Zendy; Gordana Stanković-Babić | Zendy

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Immunohistochemical detection of estrogen and progesterone receptors in the human lacrimal gland

Author(s) -

Jasmina Gligorijević,

Miodrag Krstić,

Gordana Stanković-Babić

Publication year - 2011

Publication title -

archives of biological sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.217

H-Index - 25

eISSN - 1821-4339

pISSN - 0354-4664

DOI - 10.2298/abs1102319g

Subject(s) - immunohistochemistry , lacrimal gland , estrogen , estrogen receptor , endocrinology , medicine , receptor , progesterone receptor , biology , pathology , cancer , breast cancer

The nature and extent of estrogen and progesterone action on the lacrimal gland is not known, and neither are the targets for their action. Immunohistochemical detection of estrogen and progesterone receptors in the human lacrimal glands in both sexes in different age groups was performed in this study. Twenty human lacrimal glands from autopsies were analyzed by the immunohistochemical method of cell counting and the χІ test. Estrogen and progesterone receptors were detected in the lacrimal glands of both sexes with significantly higher total and average cell counts in females (p<0,001). Estrogen and progesterone receptors are present in human lacrimal glands with age and gender dependent expression

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