Ghrelin endocrine cells in the human stomach during prenatal and early postnatal development | Zendy

Olivera Mitrović Ajtić | Zendy; Mileva Mićić | Zendy; Vera Todorović | Zendy; Goran Radenković | Zendy; Sanja Vignjević | Zendy; Dragoslava Djikić | Zendy; Mirela Budeč | Zendy; Tijana Breković | Zendy

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Ghrelin endocrine cells in the human stomach during prenatal and early postnatal development

Author(s) -

Olivera Mitrović Ajtić,

Mileva Mićić,

Vera Todorović,

Goran Radenković,

Sanja Vignjević,

Dragoslava Djikić,

Mirela Budeč,

Tijana Breković

Publication year - 2011

Publication title -

archives of biological sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.217

H-Index - 25

eISSN - 1821-4339

pISSN - 0354-4664

DOI - 10.2298/abs1101021m

Subject(s) - ghrelin , stomach , enteroendocrine cell , antrum , human stomach , endocrine system , fetus , pyloric antrum , endocrinology , medicine , biology , immunohistochemistry , pregnancy , hormone , genetics

The aim of this study was to investigate the appearance, localization and density of ghrelin cells in the human stomach during prenatal development. For this purpose the antrum and corpus of embryos, fetuses and infants are stained immunohistochemically by the streptavidin-biotin technique. The presence of P/D1 cells at 11 weeks of fetal development, their highest density during the first detection and higher density in the corpus than in antrum, and their localization in the glandular base of stomach gland, all suggest that ghrelin plays a major role in the early stages of the developing stomach

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