Immune-related health-relevant changes in natural populations of Norway rat (Rattus norvegicus Berkenhout, 1769): White blood cell counts, leukocyte activity, and peripheral organ infiltration | Zendy

Milena Kataranovski | Zendy; D. Radović | Zendy; Lidija Zolotarevski | Zendy; Aleksandra Popov Aleksandrov | Zendy; Dragan Kataranovski | Zendy

Open Access

Immune-related health-relevant changes in natural populations of Norway rat (Rattus norvegicus Berkenhout, 1769): White blood cell counts, leukocyte activity, and peripheral organ infiltration

Author(s) -

Milena Kataranovski,

D. Radović,

Lidija Zolotarevski,

Aleksandra Popov Aleksandrov,

Dragan Kataranovski

Publication year - 2009

Publication title -

archives of biological sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.217

H-Index - 25

eISSN - 1821-4339

pISSN - 0354-4664

DOI - 10.2298/abs0902213k

Subject(s) - infiltration (hvac) , immune system , biology , inflammation , white blood cell , leukocyte counts , cellular infiltration , peripheral blood , immunology , pathology , physiology , medicine , physics , thermodynamics

Basic immune-related health-relevant changes (total and differential white blood cell counts and activity, leukocyte tissue infiltration, and related pathohistology) were assessed in wild Norway rats from urban habitats. Comparative measurements were conducted in individuals of several laboratory strains of Norway rat in order to gain insight into environmental effects on the health of wild rats. Changes in leukocyte counts and activity along with tissue infiltration were noted only in wild rats, indicating systemic as well as tissue inflammation in these animals. Coincidence of these changes with chronic inflammatory pulmonary and kidney disease was observed in the majority of affected rats

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