Effect of camphor essential oil on rat cerebral cortex activity as manifested by fractal dimension changes | Zendy

Gordana Grbić | Zendy; M. Ćulić | Zendy; Ljiljana Martać | Zendy; Marina Sokóvić | Zendy; Sladjana Z. Spasić | Zendy; Dejan Djoković | Zendy

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Effect of camphor essential oil on rat cerebral cortex activity as manifested by fractal dimension changes

Author(s) -

Gordana Grbić,

M. Ćulić,

Ljiljana Martać,

Marina Sokóvić,

Sladjana Z. Spasić,

Dejan Djoković

Publication year - 2008

Publication title -

archives of biological sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.217

H-Index - 25

eISSN - 1821-4339

pISSN - 0354-4664

DOI - 10.2298/abs0804547g

Subject(s) - camphor , essential oil , cerebral cortex , fractal dimension , chemistry , anesthesia , neuroscience , medicine , biology , fractal , mathematics , chromatography , organic chemistry , mathematical analysis

The aim of our study was to investigate the effect of camphor essential oil on rat cerebral cortex activity by fractal analysis. Fractal dimension (FD) values of the parietal electrocortical activity were calculated before and after intra-peritoneal administration of camphor essential oil (450-675 μl/kg) in anesthetized rats. Camphor oil induced seizure-like activity with single and multiple spiking of high amplitudes in the parietal electrocorticogram and occasional clonic limb convulsions. The FD values of cortical activity after camphor oil administration increased on the average. Only FD values of cortical ECoG sequences were lower than those before camphor oil administration

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