Anti-genotoxic effect of aloe vera gelR on the mutagenic action of ethyl methanesulfonate | Zendy

Snežana Stanić | Zendy

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Anti-genotoxic effect of aloe vera gelR on the mutagenic action of ethyl methanesulfonate

Author(s) -

Snežana Stanić

Publication year - 2007

Publication title -

archives of biological sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.217

H-Index - 25

eISSN - 1821-4339

pISSN - 0354-4664

DOI - 10.2298/abs0703223s

Subject(s) - mutagen , ethyl methanesulfonate , genotoxicity , aloe vera , traditional medicine , toxicology , methyl methanesulfonate , positive control , chemistry , biology , toxicity , genetics , dna damage , carcinogen , medicine , mutation , dna , gene , organic chemistry

The antimutagenic effect of aloe vera gelR was investigated using the Drosophila sex-linked recessive lethal test (or SLRL test). In this assay, 3-day-old adults were treated with a direct-acting mutagen - ethyl methanesulfonate (EMS), which was the positive control. The other group of individuals of the same age was firstly treated with EMS, and then with aloe vera gelR (co-treatment). When co-treatment experiments with aloe were carried out, it was effective in reducing genotoxicity of the direct-acting mutagen.

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