Reduced growth of the adrenal zona glomerulosa after neonatal treatment of female rats with SRIH-14
Author(s) -
Verica Milošević,
Svetlana Trifunović,
Milka Sekulić
Publication year - 2006
Publication title -
archives of biological sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.217
H-Index - 25
eISSN - 1821-4339
pISSN - 0354-4664
DOI - 10.2298/abs0602001m
Subject(s) - zona glomerulosa , endocrinology , medicine , biology , angiotensin ii , blood pressure
array of biological actions, including the inhibition of hormone secretion, modulation of neural transmission and regulation of cell growth (F l o r i o et al., 1999). At the periphery, SRIH inhibits the secretion of several non-pituitary hormones such as insulin, glucagon, gastrin, secretin and aldosterone (R e i c h l i n , 1983; M i l o š e v i ć , 1999). Within the nervous system, SRIH acts as a neuromodulator, affecting neuroendocrine, motor, and cognitive functions (R e i c h l i n , 1983; E p e l b a u m et al., 1994). Because of its ability to inhibit secretory functions of various organs, its therapeutic value in clinical conditions is recognized and used.
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