Open AccessComparative study on the antibacterial activity of volatiles from sage (Salvia officinalis L.)
Author(s) -
Dragana Mitić-Ćulafić,
Branka VukovićGačić,
Jelena KneževićVukčević,
Slaviša Stanković,
Draga Simić
Publication year - 2005
Publication title -
archives of biological sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.217
H-Index - 25
eISSN - 1821-4339
pISSN - 0354-4664
DOI - 10.2298/abs0503173m
Subject(s) - sage , salvia officinalis , antibacterial activity , minimum inhibitory concentration , minimum bactericidal concentration , essential oil , microbiology and biotechnology , bacillus subtilis , agar diffusion test , chemistry , population , gram , staphylococcus aureus , biology , escherichia coli , bacteria , traditional medicine , antimicrobial , officinalis , food science , botany , biochemistry , medicine , physics , genetics , environmental health , nuclear physics , gene
Antibacterial activity of volatiles from sage against Gram-positive and Gram-negative bacteria from the ATCC collection was screened with the disk diffusion test. The essential oil and its fractions showed a significant antibacterial effect against S. aureus and B. subtilis. The minimum inhibitory concentrations were 1.25-2.5 μL/mL for S. aureus and 0.15-2.5 μL/mL for B. subtilis. The effect on S. aureus was bactericidal, while initial bactericidal effect on B. subtilis was impaired by the presence of a resistant fraction of the population, probably endospores. The results obtained with wild type and permeable strains of E. coli and S. typhimurium indicate that transport through the cell wall limits the antibacterial effect of sage volatiles
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