Determinación de la asociación del polimorfismo de la Apolipoproteína E (Apo E) relacionada con la presencia de placa aterosclerótica coronaria.

The polimorfism of the Apolipoprotein E (Apo E), it plays a key paper in the lipids metabolism and the coronary illness. This study looked for to identify specific polimorfisms of Apo E for PCR-RFLP and to determine the association in these ways alelicas with the presence of plaque atheroesclerotic. A total of 122 patients was analyzed between 29 and 85 years old, with angina or sharp infart of the miocardial where the occlusion presence was determined by coronary arteriographic. Of the total of analyzed patients, alone 48.4% presented an obstruction degree bigger than 70%. Of these patients 40 were men and 19 women. When establishing the association among obstruction degrees and polimorfismo ofApoE stratified for the genders, a