El papel del biofilm en el proceso infeccioso y la resistencia

Infectious process and resistance biofilm role. Biofilm is a cell population which grows up together in a wrapped surface in a exopolysaccharide matrix which protects them of antibiotic attacks. More than 60% of all microbial infection is caused by Biofilm, to raise the resistance of these antimicrobial communities there are several mechanisms among others; antibiotic inactivity by extracellular polymerous or enzymatic alteration, grow rate diminished due to nutrient limitation, phenotypic changes in bacterial cells as a result of acquisition of resistance gene into biofilm and the persistence of a small cell group in bacterial community. The prognostic to treat and quit out biofilms is not encouraging in the immediate future. Is necessary and urgent to develop new medicines to counteract infectious on which