ANTIBACTERIAL AND CYTOGENETIC EFFECT OF Cassia italica LEAF EXTRACT ON ALBINO MALE MICE | Zendy

Ebtehal H. Al-Naimy | Zendy; M. AL-Amery | Zendy; Ruqia M. Al-Azy | Zendy

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ANTIBACTERIAL AND CYTOGENETIC EFFECT OF Cassia italica LEAF EXTRACT ON ALBINO MALE MICE

Author(s) -

Ebtehal H. Al-Naimy,

M. AL-Amery,

Ruqia M. Al-Azy

Publication year - 2010

Publication title -

journal of al-nahrain university-science

Language(s) - English

Resource type - Journals

eISSN - 2519-0881

pISSN - 1814-5922

DOI - 10.22401/jnus.13.4.18

Subject(s) - cassia , distilled water , tetracycline , metaphase , colchicine , biology , decoction , bone marrow , microbiology and biotechnology , traditional medicine , chemistry , antibiotics , botany , biochemistry , medicine , immunology , pathology , chromatography , alternative medicine , traditional chinese medicine , genetics , gene , chromosome

This study was designed to evaluate the antibacterial and cytogenetic effect of Cassia italica (Senna) on metaphase index and micronucleous formation in polychromatic erythrocytes of bone marrow cells of mice. Results showed that Cassia italica leaves methanolic extract caused a significant inhibition in growth of E.coli and Staphylococcus auerous and Candida albicans especially at high concentrations in comparison with the negative control (Distilled water) and positive controls (Tetracycline). On the other hand the results showed that Cassia italica extract caused a significant increase in metaphase index and a significant decrease in micronucleous formation in bone marrow of mice in comparison with the negative control (Distilled water) and positive controls (Cyclophosphomide).

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