Open AccessSYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL ACTIVITY OF SOME METAL IONS WITH 2-THIOACETIC-5-PHENYL-1,3,4- OXADIAZOLE
Author(s) -
Hanan Ibraheem,
Hadeel Adel,
Ahmed Ahmed,
Nadia Salih,
Jumat Salimon,
Abdualbasit͏͏͏͏͏͏͏͏͏͏͏͏͏͏͏͏͏͏͏ Graisa,
Yang Farina,
Emad͏͏͏͏͏͏͏͏͏͏͏͏͏͏͏͏͏͏͏ Yousif
Publication year - 2010
Publication title -
journal of al-nahrain university-science
Language(s) - English
Resource type - Journals
eISSN - 2519-0881
pISSN - 1814-5922
DOI - 10.22401/jnus.13.3.06
Subject(s) - oxadiazole , copper , monomer , metal , chemistry , spectroscopy , fourier transform infrared spectroscopy , ligand (biochemistry) , nuclear magnetic resonance spectroscopy , magnetic susceptibility , proton nmr , carbon 13 nmr , antimicrobial , crystallography , metal ions in aqueous solution , nuclear chemistry , polymer chemistry , stereochemistry , organic chemistry , polymer , biochemistry , physics , receptor , quantum mechanics
New metal complexes of the ligand 2-thioacetic-5-phenyl-1,3,4-oxadiazole with the metal ions Ni(II), Cu(II), Zn(II), Cd(II) and Sn(II) were prepared in alcoholic medium. The prepared complexes were characterized by FTIR Spectroscopy, electronic spectroscopy, mass spectroscopy 1H NMR, 13C NMR, magnetic susceptibility and conductivity measurements. From the spectral measurements, monomer structures for the complexes were proposed. Square planar geometry was proposed for the copper complex. The other complexes were proposed to be tetrahedral. Preliminary in vitro tests for antimicrobial activity show that all prepared compounds display good activity to Staphylococcus aureus, Escherishia coli, Pseudononas aeroginosa and Cndida albicans.
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