The use of the cyberknife stereotactic radiosurgery system for the treatment of intracranial and extracranial residual or recurrent chordoma

LEE M, LIEBERSON RE, SOLTYS SG, GIBBS IC, JR JRA, CHANG SD The use of the cyberknife stereotactic radiosurgery system for the treatment of intracranial and extracranial residual or recurrent chordoma. J Bras Neurocirurg 20 (2): 102-109, 2009 size reduction. However, 5 out of the 17 cases showed progression with one developing a new lesion at a lower cervical vertebra despite good local control. None of the patients with tumor control developed new neurological deficits, but 4 of the 5 cases with tumor progression showed worsening neurological deficits. There was no radiation associated complications. Conclusions: Good tumor control rates can be achieved with no significant morbidity with CyberKnife based stereotactic radiosurgery. Cases with poor control tended to have complex multiple surgical resections. Longer follow-up in larger series is required to adequately compare this technique with other forms of radiation therapy.