PREPARATION AND CHARACTERIZATION OF TOLTERODINE TARTRATE PRONIOSOMES | Zendy

Adim Ekene Ugochukwu | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

PREPARATION AND CHARACTERIZATION OF TOLTERODINE TARTRATE PRONIOSOMES

Author(s) -

Adim Ekene Ugochukwu

Publication year - 2017

Publication title -

universal journal of pharmaceutical research

Language(s) - English

Resource type - Journals

ISSN - 2456-8058

DOI - 10.22270/ujpr.v2i2.r1

Subject(s) - tolterodine , coacervate , chromatography , materials science , chemistry , nanotechnology , chemical engineering , medicine , alternative medicine , pathology , overactive bladder , engineering

The present work deals with the preparation of Tolterodine tartrate proniosome formulations by coacervation phase separation method by using different surfactants in different ratios. The prepared proniosomal formulations were evaluated for vesicle size, rate of spontaneity, encapsulation efficiency, drug content etc. In vitro release study was conducted and it indicated that, increases in liphophilicity of surfactants decreases release of Tolterodine tartrate from proniosomal formulations. Stability studies were performed at optimized formulation PG4, indicated that, the prepared formulations remain stable at room and refrigeration temperature.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research