Open Access2019-nCoV/COVID-19 - Approaches to Viral Vaccine Development and Preventive Measures
Author(s) -
Muhammad Bilal,
Muhammad Shahzad Nazir,
Roberto ParraSaldívar,
Hafiz M.N. Iqbal
Publication year - 2020
Publication title -
journal of pure and applied microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.149
H-Index - 16
eISSN - 2581-690X
pISSN - 0973-7510
DOI - 10.22207/jpam.14.1.05
Subject(s) - covid-19 , case fatality rate , pandemic , coronavirus , risk assessment , medicine , epidemiology , identification (biology) , virology , intensive care medicine , computer science , outbreak , biology , disease , infectious disease (medical specialty) , pathology , computer security , botany
The severity assessment of COVID-19 and transmissibility of newly emerged novel-Coronavirus (2019-nCoV) can effectively help and support to quantify the ongoing pandemic risks. Among several epidemiological measures against COVID-19 severity, the case fatality risk (CFR) assessment is an important measure to track record the overall proportion/ratio of the cumulative number of infected patients with the known outcome (confirmed, recovered, or deceased). Considering the ongoing fatality rate, several case-based preventive measures, Coronavirus protein visualization, and approaches to viral vaccine development are discussed herein. The prompt identification of high-risk entities to confront the uncertainty in the risk of death using the approaches highlighted, herein, is of utmost requirement to tackle the current COVID-19 severity. Moreover, the protein visualization available at the viral surface/ body can give further insight into the appropriate vaccine development.
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