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Human cytomegalovirus (CMV) as a member of the herpes virus family is one of the most common infecting viruses in humans. The prevalence of congenital CMV infection varies from 0.2% to 2% (). In developing countries, the reported prevalence of congenital CMV infection varies dramatically within and between populations, with some recorded prevalence ranged from 6.1% Study the Impact of Cytomegalovirus (CMV) Infection and the Risk Factor for Liver Dysfunction in Saudi Patients