Resistance in Gram Negative Organisms: A Need for Antibiotic Stewardship
Author(s) -
Areena Hoda Siddiqui,
Poonam Verma
Publication year - 2018
Publication title -
journal of pure and applied microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.149
H-Index - 16
eISSN - 2581-690X
pISSN - 0973-7510
DOI - 10.22207/jpam.12.2.30
Subject(s) - gram , antibiotic stewardship , stewardship (theology) , antibiotics , gram negative bacteria , antibiotic resistance , resistance (ecology) , microbiology and biotechnology , antimicrobial stewardship , business , biology , bacteria , ecology , political science , genetics , escherichia coli , politics , law , gene
Antibiotic resistance is increasing in Gram Negative organisms. It is important to know the antibiogram of the hospital to start empirical therapy. It can serve as a reference to clinician looking for information on antibiotic resistance. A retrospective analysis of the isolates obtained from January 2016 to December 2016 was performed. Samples were processed as per CLSI guideline. A total of 718 isolates were obtained. These were analysed for the prevalence of MDR/XDR/PDR. It was found that XDR isolates are prevalent in our teaching hospital. The study showed an emergence in pan drug resistant isolates. The knowledge of local antibiogram along with strong antibiotic stewardship program can help in guiding antibiotic therapy.This reduces antibiotic pressure among organisms and hence development of resistance.
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