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Potentiated Therapeutic Angiogenesis by Primed Human mesenchymal Stem Cells in a Mouse Model of Hindlimb Ischemia
Author(s) -
Eun Ju Lee,
HwanWoo Park,
Hyo-Jin Jeon,
HyoSoo Kim,
MiSook Chang
Publication year - 2013
Publication title -
regenerative medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.572
H-Index - 63
eISSN - 1746-076X
pISSN - 1746-0751
DOI - 10.2217/rme.13.17
Subject(s) - mesenchymal stem cell , therapeutic angiogenesis , angiogenesis , paracrine signalling , transplantation , in vivo , cell therapy , medicine , cancer research , ischemia , priming (agriculture) , stem cell , immunology , neovascularization , microbiology and biotechnology , pathology , biology , botany , receptor , germination
Human bone marrow-derived mesenchymal stem cells (hMSCs) are advantageous for cell-based therapy to treat ischemic diseases owing to their capacity to secrete various paracrine factors with potent angiogenic activity.

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