Common genetic polymorphisms of adenosine A2A receptor do not influence response to regadenoson | Zendy

Mark Berlacher | Zendy; Ronald Mastouri | Zendy; Santosh Philips | Zendy; Todd C. Skaar | Zendy; Rolf P. Kreutz | Zendy

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Common genetic polymorphisms of adenosine A2A receptor do not influence response to regadenoson

Author(s) -

Mark Berlacher,

Ronald Mastouri,

Santosh Philips,

Todd C. Skaar,

Rolf P. Kreutz

Publication year - 2017

Publication title -

pharmacogenomics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.541

H-Index - 91

eISSN - 1744-8042

pISSN - 1462-2416

DOI - 10.2217/pgs-2016-0178

Subject(s) - regadenoson , myocardial perfusion imaging , medicine , cardiology , perfusion , adenosine a2a receptor , hemodynamics , heart rate , genotyping , adenosine receptor , blood pressure , genotype , receptor , biology , agonist , biochemistry , gene

Hemodynamic response to regadenoson varies greatly, and underlying mechanisms for variability are poorly understood. We hypothesized that five common variants of adenosine A2A receptor (ADORA2A) are associated with altered response to regadenoson.

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