Open AccessFunctionalization of Mesoporous Silica Nanoparticles with a Cell-Penetrating Peptide to Target Mammalian Sperm in vitro
Author(s) -
Natalia Barkalina,
Céline Jones,
Helen Townley,
Kevin Coward
Publication year - 2015
Publication title -
nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.947
H-Index - 109
eISSN - 1748-6963
pISSN - 1743-5889
DOI - 10.2217/nnm.14.235
Subject(s) - surface modification , mesoporous silica , peptide , in vitro , sperm , nanoparticle , chemistry , biophysics , nanotechnology , microbiology and biotechnology , mesoporous material , materials science , biochemistry , biology , catalysis , botany
This study aimed to investigate the effects of actively targeting mesoporous silica nanoparticles (MSNPs) toward mammalian sperm with a cell-penetrating peptide (C105Y), with subsequent analysis of binding rates and nano-safety profiles.
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