Open AccessIn Vivo Evaluation of Paclitaxel-Loaded Lipid Nanocapsules After Intravenous and Oral Administration on Resistant Tumor
Author(s) -
AnneClaire Groo,
M Bossière,
Laury Trichard,
Pierre Legras,
JeanPierre Benoît,
Frédéric Lagarce
Publication year - 2015
Publication title -
nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.947
H-Index - 109
eISSN - 1748-6963
pISSN - 1743-5889
DOI - 10.2217/nnm.14.124
Subject(s) - nanocapsules , paclitaxel , in vivo , pharmacology , oral administration , medicine , chemotherapy , materials science , nanotechnology , biology , microbiology and biotechnology , nanoparticle
The aim of the present work was to encapsulate paclitaxel (Ptx) in various lipid nanocapsules (LNCs) formulations and then to compare their pharmacokinetics and efficacy on a subcutaneous isograft model in rats.
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