Chemorad Nanoparticles: A Novel Multifunctional Nanoparticle Platform for Targeted Delivery of Concurrent Chemoradiation
Author(s) -
Andrew Z. Wang,
Kai P. Yuet,
Liangfang Zhang,
Frank Gu,
MinhPhuong HuynhLe,
Aleksandar F. RadovicMoreno,
Philip W. Kantoff,
Neil H. Bander,
Róbert Langer,
Omid C. Farokhzad
Publication year - 2010
Publication title -
nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.947
H-Index - 109
eISSN - 1748-6963
pISSN - 1743-5889
DOI - 10.2217/nnm.10.6
Subject(s) - nanoparticle , nanotechnology , materials science
The development of chemoradiation - the concurrent administration of chemotherapy and radiotherapy - has led to significant improvements in local tumor control and survival. However, it is limited by its high toxicity. In this study, we report the development of a novel NP (nanoparticle) therapeutic, ChemoRad NP, which can deliver biologically targeted chemoradiation.
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