Open AccessPolymeric Glabrescione B Nanocapsules for Passive Targeting of Hedgehog-dependent Tumor Therapy In Vitro
Author(s) -
Cinzia Ingallina,
Pedro M. Costa,
Francesca Ghirga,
Rebecca Klippstein,
Julie Wang,
Simone Berardozzi,
Naomi O. Hodgins,
Paola Infante,
Steven M. Pollard,
Bruno Botta,
Khuloud T. AlJamal
Publication year - 2017
Publication title -
nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.947
H-Index - 109
eISSN - 1748-6963
pISSN - 1743-5889
DOI - 10.2217/nnm-2016-0388
Subject(s) - nanocapsules , in vitro , hedgehog , pharmacology , medicine , materials science , chemistry , nanotechnology , nanoparticle , biochemistry , gene
With the purpose of delivering high doses of glabrescione B (GlaB) to solid tumors after systemic administration, long-circulating GlaB-loaded oil-cored polymeric nanocapsules (NC-GlaB) were formulated.
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