Improving Lipids With Prescription Icosapent Ethyl After Previous Use of Fish Oil Dietary Supplements | Zendy

K. J. Reddy | Zendy; Sumita Chowdhury | Zendy

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Improving Lipids With Prescription Icosapent Ethyl After Previous Use of Fish Oil Dietary Supplements

Author(s) -

K. J. Reddy,

Sumita Chowdhury

Publication year - 2016

Publication title -

future cardiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.392

H-Index - 33

eISSN - 1744-8298

pISSN - 1479-6678

DOI - 10.2217/fca-2015-0009

Subject(s) - eicosapentaenoic acid , medicine , fish oil , dyslipidemia , statin , medical prescription , coronary artery disease , adverse effect , omega 3 fatty acid , ethyl ester , pharmacology , gastroenterology , fatty acid , docosahexaenoic acid , disease , fish <actinopterygii> , biochemistry , polyunsaturated fatty acid , biology , chemistry , organic chemistry , fishery

Managing dyslipidemia can be challenging in patients with statin intolerance. We describe the lipid effects of icosapent ethyl 4 g/day (high-purity prescription omega-3 eicosapentaenoic acid) in two coronary artery disease patients with statin intolerance who were self-treating with fish oil dietary supplements. After initiating icosapent ethyl, improvements were noted in the first and second patients, respectively, in total cholesterol (-12%; -21%), LDL cholesterol (-3%; -24%), triglycerides (-34%; -16%), non-HDL cholesterol (-12%; -22%), the omega-3 index (+42%; +8%) and eicosapentaenoic acid levels (+275%; +138%). Icosapent ethyl was well tolerated with no adverse events reported. These cases demonstrated favorable lipid effects with prescription icosapent ethyl treatment that may help optimize the care of high-risk coronary artery disease patients with statin intolerance.

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