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Transplantation of 3D Scaffolds Seeded with Human Embryonic Stem Cells: Biological Features of Surrogate Tissue and Teratoma-Forming Potential
Author(s) -
Justin G. Lees,
Sue Anne Lim,
Tristan I. Croll,
Georgia Williams,
Sylvia Lui,
Justin J. CooperWhite,
Leon R. McQuade,
Bagyalakshmi Mathiyalagan,
Bernard E. Tuch
Publication year - 2007
Publication title -
regenerative medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.572
H-Index - 63
eISSN - 1746-076X
pISSN - 1746-0751
DOI - 10.2217/17460751.2.3.289
Subject(s) - embryonic stem cell , transplantation , stem cell , teratoma , tissue engineering , biology , pathology , anatomy , microbiology and biotechnology , medicine , biomedical engineering , surgery , biochemistry , gene
To generate complex surrogate tissue by transplanting 3D scaffolds seeded with human embryonic stem cells (hESCs) between the liver lobules of severe combined immunodeficient (SCID) mice and to assess the teratoma-forming potential.

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